Keywords

• Cholecalciferol 67-97-0
• lowest price Vitamin d3
• good supplier 67-97-0

Quick Details

• ProName: Cholecalciferol 67-97-0 lowest price V...
• CasNo: 67-97-0
• Molecular Formula: C27H44O
• Appearance: white powder
• Application: Food grade,Nutritional Supplements.
• DeliveryTime: 5-7 working days
• PackAge: Bottle, Drum, Vacuum Packed, Plastic b...
• Port: China major port
• ProductionCapacity: 55 Metric Ton/Month
• Purity: 99%
• Storage: Sealed, dry and refrigerated
• Transportation: By Express,Air,Sea
• LimitNum: 1 Kilogram
• Related Substances: Cholecalciferol
• Residue on Ignition: <5
• Heavy Metal: <10ppm
• Valid Period: 2 Years
• Product Name: Vitamin d3
• Specification: 99%
• Appearance: white powder-off white powder
• EINECS: 200-673-2
• Sample: 5-10g
• MOQ: 1KG
• Test Method: HPLC
• Brand Name: QUANAO

Superiority

Cholecalciferol lowest price Vitamin d3 good supplier 67-97-0

Vitamin D3 is used as an essential mediator of intestinal calcium absorption and bone calcium metabolism. It is also used as a therapeutic vitamin. Further, it is used as a nutritional supplement and to fortify foods. In addition to this, it is used as pharmaceutical drug and used in the treatment of respiratory diseases involving chronic inflammation such as asthma.

Cholecalciferol is a naturally occuring form of vitamin D. Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells. Cholecalciferol is an activator of VDR.

Cholecalciferol acts as a hormone precursor since it requires two stages of metabolism: first to 25-hydroxycholecalciferol; then to 1α, 25-dihydroxycholecalciferol. One unit (U.S.P. or international) is defined as the activity of 0.025 μg of vitamin D3 contained in the USP vitamin D reference standard.

Cholecalciferol is sourced either through the diet or exposing skin to ultraviolet rays. Oral administration of vitamin D₃ is readily absorbed and is stored in adipose tissue.

Cholecalciferol (Vitamin D₃) is known for the maintenance of normal skeleton architecture and mineral homeostasis. Vitamin D₃ is synthesized from 7-dehydrocholesterol [CAS: 434-16-2] in the skin under the influence of UV light, or it is obtained from food, especially fatty fish. The transformation (hydroxylation) of vitamin D₃ is catalyzed by enzymes in the liver and the kidney to produce calcitriol [C3078] (other name: 1α,25-dihydroxyvitamin D₃), the active form of vitamin D₃. Calcitriol is active in the regulation of the absorption of calcium from the gastrointestinal tract.

Details

Vitamin D₃ is a biologically inactive precursor to calcitriol (Item No. 71820) that is converted to active metabolites in vivo. Vitamin D₃ is obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol (Item No. 14612) to previtamin D₃ by UVB radiation, followed by isomerization to vitamin D₃. Vitamin D₃ can then be converted to 25-hydroxy vitamin D₃ (Item No. 9000683) in the liver by the cytochrome P450 (CYP) isoform CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney. Formulations containing vitamin D₃ have been used in the treatment of osteoporosis.