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CAS NO.58-85-5
2%(2-24)Kilogram2%(25-99)Kilogram98%(1-9)Kilogram98%(10-25)Kilogram
Top quality 58-85-5 Vitamin B7 On Sale High Purity D-biotin
Biotin is a water-soluble vitamin, also known as vitamin B7. Biotin is an essential coenzyme for five carboxylases in mammalian cells, which play key roles in the metabolism of glucose, amino acids and fatty acids (Zempleni, 2014). Biotin is also used in biochemistry in affinity purification of proteins in the biotin-avidin and biotin-streptavidin systems. Herein, free biotin is used in the elution step to release the recombinant protein from the resin (Diamandis and Christopoulos, 1991).
Biotin is an essential coenzyme for certain carboxylases. It is used to modify histones and regulate gene transcription. Biotin-dependent carboxylases are involved in fatty acid and amino acid synthesis, and play a role in gluconeogenesis.In addition, biotin is used in biotechnological applications such as DNA-hybridization, flow cytometry, affinity purification, and identification of protein-protein interactions and post-translational modifications.
Biotin is a growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.
Alternate Name | D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H |
---|---|
Appearance | White to off-white solid |
CAS # | 58-85-5 |
Molecular Formula | C??H??N?O?S |
Molecular Weight | 244.31 |
Purity | ≥98% |
Solubility | DMSO (>40 mg/ml) |
SMILES | C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2 |
InChi | nChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1 |
InChi Key | YBJHBAHKTGYVGT-ZKWXMUAHSA-N |
PubChem CID | 171548 |
MDL Number | MFCD00005541 |
Handling | Protect from air and light |
Storage Conditions | 4°C |
Shipping Conditions | RT |
USAGE | For Research Use Only! Not For Use in Humans. |