Keywords

• Bitter Sophora Root Extract 98% Matrine 519-02-8
• low price 519-02-8
• Matrine On Sale

Quick Details

• ProName: Bitter Sophora Root Extract 98% Matrin...
• CasNo: 519-02-8
• Molecular Formula: C15H24N2O
• Appearance: White Powder
• Application: 1. Used For Insecticide Bitter Sophora...
• DeliveryTime: 7-9
• PackAge: 1kg with double plastic container insi...
• Port: Shanghai
• ProductionCapacity: 100000000 Kilogram/Year
• Purity: 98%
• Storage: Stored in a clean, cool, dry area; kee...
• Transportation: Express, air, sea.
• LimitNum: 100 Kilogram
• Plant of Origin: Sophora Root Extract 98% powder Matrin...
• Testing Method: HPLC
• Product Ecification: 98%
• Heavy Metal: ＜10ppm
• Voluntary Standards: Chinese standard
• Product Name: Sophora Root Extract 98% powder Matrin...
• Appearance: White Powder
• Extraction Type: Solvent Extraction
• Place of Origin: Shaanxi， China
• Grade: Pharmaceutical and food grade
• MOQ: 1kg
• Package: 1kg/ Bag 25kg/drum
• Certificate: ISO9001/Halal/Kosher
• Specification: 100% Natural Sophora Root Extract
• Shelf Life: 2 Years

Superiority

Bitter Sophora Root Extract 98% Matrine low price 519-02-8 Matrine  On Sale

Matrine is an alkaloid found in S. flavescens roots that has diverse biological activities. It inhibits LPS-induced splenocyte proliferation and release of IL-1 and IL-6 from mouse peritoneal macrophages in vitro. In mice, administration of matrine inhibits the development of LPS-induced hepatitis in a dose-dependent manner. Matrine reduces production of the hepatitis B surface antigen (HBsAG) and serum antigen (HBeAG) with IC₅₀ values of 0.75 and 3.35 mg/mL, respectively, in vitro and inhibits viral replication in a duck model of hepatitis B. In vitro, matrine inhibits angiotension II-induced hyperplastic growth of cardiac fibroblasts in a dose-dependent manner.Matrine also inhibits proliferation of melanoma, breast, and colon cancer cells with IC₅₀s ranging from 0.769-2.758 mg/ml.

Matrine is a biologically active alkaloid isolated from the root of the saphoro plant. It inhibits LPS-induced splenocyte proliferation and release of IL-1 and IL-6 from mouse peritoneal macrophages in vitro. Matrine has been studied for possible antiviral efficacy against hepatitis B and C, as well as impact against some skin diseases and forms of cancer.

Matrine (519-02-8) is a natural product found in the plant Sophora flavescens.  It has been found to possess myriad biological activities including a positive inotropic effect, reduced glucose intolerance and hepatic steatosis in a mouse model via activation of HSP72, various anti-cancer effects.  Matrine has also recently been shown to induce RIP3-dependent necroptosis in cholangiocarcinoma cells.

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