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Hot sale Silibinin Offer Milk Thistle Extract 80% Silibinin 22888-70-6 in China

CAS NO.22888-70-6

  • FOB Price: USD: 248.00-253.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
  • Available Specifications:

    80%(1-10)Kilogram80%(10-25)Kilogram80%(25-100)Kilogram

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Product Details

Keywords

  • Hot sale Silibinin
  • Offer Milk Thistle Extract 80% Silibinin
  • 22888-70-6 in China

Quick Details

  • ProName: Hot sale Silibinin Offer Milk Thistle ...
  • CasNo: 22888-70-6
  • Molecular Formula: C29H50O
  • Appearance: White Fine Powder
  • Application: 1. It is widely used in medicine, heal...
  • DeliveryTime: 7-9
  • PackAge: 1kg with double plastic container insi...
  • Port: SHANGHAI
  • ProductionCapacity: 100000000 Kilogram/Year
  • Purity: 80%
  • Storage: Stored in a clean, cool, dry area; kee...
  • Transportation: Express, sea, land, air
  • LimitNum: 1 Kilogram
  • Plant of Origin: Milk Thistle Extract
  • Testing Method: UV
  • Product Ecification: 80%
  • Heavy Metal: ＜5ppm
  • Voluntary Standards: Chinese standard
  • Product Name: Milk Thistle Extract 80% Silibinin
  • Appearance: White Fine Powder
  • Extraction Type: Solvent Extraction
  • Grade: Food Grade/Cosmetic Grade， Cosmetics g...
  • Model Number: 80%
  • Test Method: UV
  • MOQ: 1 Kg
  • Shelf Life: 2 Years
  • Particle Size: 100% Pass 80 Mesh

Superiority

Hot sale Silibinin Offer Milk Thistle Extract 80% Silibinin 22888-70-6 in China

Silybin is the major flavonolignan found in milk thistle (S. marianum). It inhibits wild mushroom tyrosinase (IC50 = 1.7 μM).Silybin scavenges superoxide radicals (IC50 = 55.2 μM) and inhibits lipid peroxidation in vitro (IC50 = 73.92 μM).

Silybin is an inhibitor of a wide variety of proteins, many of which are heavily involved in xenobiotic efflux and metabolism. Silybin is an inhibitor of P-glycoprotein-mediated cellular efflux and also inhibits xenobiotic oxidation by the CYP (cytochrome P450) superfamily of enzymes. This helps to contribute the apoptotic activity of this compound, which has been shown to be effective against a wide variety of cancer cell lines. Silybin is an inhibitor of 5-LO.

The major active component of silymarin flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum; it is used in the treatment of HEPATITIS; LIVER CIRRHOSIS; and CHEMICAL AND DRUG INDUCED LIVER INJURY, and has antineoplastic activity; silybins A and B are diastereomers.

Name

Silibinin (Silybin)

Synonyms

Molecular Structure

22888 70 6 - Silibinin (Silybin) CAS 22888-70-6

Molecular Formula

C25H22O10

Molecular Weight

482.44

CAS Number (Or Watson Number for Non-CAS Products)

22888-70-6

EINECS

Appearance

Specs/Standards

Enterprise Standard

Details

Catalogue Number S465855
Chemical Name Silybin A
Synonyms (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; 3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-4-chromanone; [2R-[2α,3β,6(2R*,3R*)]]-2-[2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; Silybin; 1,4-Benzodioxin, 4H-1-benzopyran-4-one deriv.; 7C3MT; Mepasil; Silibinin; Silibinin A; Silliver; Silybin b1; Silybine; Silybum substance E6; Silymarin I; Silymarin MZ 80; Silymarine I
CAS Number 22888-70-6
Alternate CAS # Silybin B: 142797-34-0 / Diastereomer Mixture: 802
Molecular Formula C??H??O??
Appearance Pale Yellow Solid
Melting Point 173-176°C
Molecular Weight 482.44
Solubility Acetone (Sparingly), DMSO, Methano (Sparingly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications Silybin A is the 2R, 3R, 7‘R, 8‘R isomer of Silybin (S465850); a natural occurring flavolignan that exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells.
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