Keywords

• 65277-42-1 in stock
• Ketoconazole High quality
• Ketoconazole on hot selling

Quick Details

• ProName: 65277-42-1 in stock Ketoconazole High ...
• CasNo: 65277-42-1
• Molecular Formula: C17H20ClF2N3O3
• Appearance: white powder
• Application: Health care grade,API,
• DeliveryTime: 5-7 working days
• PackAge: Bottle, Drum, Vacuum Packed, Plastic b...
• Port: China major port
• ProductionCapacity: 55 Metric Ton/Month
• Purity: 99%
• Storage: Sealed, dry and refrigerated
• Transportation: By Express,Air,Sea
• LimitNum: 1 Kilogram
• Related Substances: Ketoconazole
• Residue on Ignition: <5
• Heavy Metal: <10ppm
• Valid Period: 2 Years
• Active Ingredient: Ketoconazole
• Specification: 99%
• Einecs No.: 265-667-4
• Application: Health care grade，API
• Sample: 5-10g
• MOQ: 1KG
• Place of Origin: Shaanxi， China
• Brand Name: QUANAO

Superiority

65277-42-1 in stock Ketoconazole High quality Ketoconazole on hot selling

Ketoconazole is a broad-spectrum triazole antifungal agent that has activity against C. albicans, C. krusei, C. tropicalis, C. glabrata, C. parapsilosis, C. neoformans, and A. fumigatus strains (IC₅₀s = 0.031-8 µg/ml).It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase, which arrests ergosterol (Item No. 19850) biosynthesis at the fungal membrane. Ketoconazole also inhibits human CYP3A4 (IC₅₀ = 0.54 µM). Formulations containing ketoconazole have been used in the treatment of fungal infections.

Ketoconazole is an inhibitor of cytochrome P450c17. Enhances the formation of myelin basic protein-positive oligodendrocytes from oligodendrocyte progenitor cells in vitro and promotes remyelination in vivo. Also an antifungal agent. Brain penetrant.

Ketoconazole is an imidazole-containing small molecule inhibitor of cytochrome P-450-dependent steps in the biosynthesis of steroid hormones; also inhibits TXA Synthase (thromboxane synthetase) and 5-LO (5-lipoxygenase) activity. Ketoconazole exhibits antimetastatic, antineoplastic, and antipsoriatic activity. Inhibition of 5-LO (5-lipoxygenase) by Ketoconazole interrupts arachidonic acid (sc-200770)-derived leukotriene production, which was correlated to a suppression of leukotriene-mediated anaphylactic bronchoconstriction in guinea pigs. Ketoconazole is described as reducing platelet cellular levels of thromboxane A₂, suppressing thromboxane A₂-mediated increase of microvascular permeability in response to ischemia insults. Ketoconazole produces an antiandrogen effect through inhibition of adrenocorticoid biosynthesis, suppressing the adrenal secretion of androgens and attenuating cortisol response. Ketoconazole is an inhibitor of CYP17A1, CYP3A4 and CYP3A5.

Details

Raw material 99% Ketoconazole powder price for soap cas 65277-42-1

Product information

       Ketoconazole is a synthetic antifungal used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral.

Product Function

1.Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.
2.Topical ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin. 

Product Application

1. Anti-Hair loss 
Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor has been used off label to treat and rogenic alopecia. The antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.Limited clinical studies suggest ketoconazole shampoo used either alone or in
combination with other treatments may be useful in reducing hair loss. 
2.At least one study has been performed showing that ketoconazole may be useful in temporarily reducing erectile function in postoperative penile surgery patients.
3.Veterinary use 
Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored tablets that may need to be cut to smaller size for correct dosage. 

Company information

FAQ:

Q1: Can I get some samples
A: Yes, free samples(5-10g or enough to detection) are available for most of our products, you only need to pay the shipping cost.

Q2: How to confirm the quality before orders
A: Two ways, either by free samples, or send us the detailed specifications, we will arrange the production as per your 
requirement.

Q3: What's your MOQ
A: Normally 1 kg, but smaller quantity is also acceptable for some special products.
 
Q4: How about discount
A: Mainly based on quantity, also some promotional products with special discount from time to time.

Q5. What's the delivery lead time
A: 2-3 working days after payment.
 
Q6: How to make order & payment
A: Proforma invoice will be sent after your confirmation of the order, We can accept payment by T/T, ,Transfer Wise and MoneyGram.