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CAS NO.520-26-3
99%(25-50)Kilogram99%(50-100)Kilogram
Offer Hesperidin powder factory Hesperidin 520-26-3 good supplier
Hesperidin is a flavanone rutinoside first isolated from citrus peels. It is metabolized by intestinal bacteria to an aglycone form, hesperetin (Item No. 10006084), which is thought to be more bioavailable due to reduced polarity that allows for increased cell permeability. At 100 µM, hesperidin has been shown to increase the cytotoxicity of doxorubicin (Item No. 15007) on MCF-7 and HeLa cancer cells in vitro by inhibiting cell cycle progression and upregulating apoptosis. It also is reported to produce estrogenic effects, decreasing serum and hepatic lipid concentrations and reducing osteoporosis in ovariectomized rats. Hesperidin produces free radical scavenging activity in various in vitro antioxidant assays.
Hesperidin (glycoside) is a flavonoid substance which has flavanone oxygen glycoside structure. It is weakly acidic with pure being white needle-like crystals. It is also the main component of vitamin P.
After the hydrogenation, hesperidin becomes a natural sweetener, dihydrochalcone, whose sweetness is 1,000 times as high as sucrose. It can be used as a functional food for application. Hesperidin has a variety of biological characteristics. Modern research has found that: hesperidin has various effects such as antioxidant, anti-cancer, anti-mildew, anti-allergy, lowering blood pressure, inhibiting oral cancer and esophageal cancer, maintenance of osmotic pressure, increasing capillary toughness, and lowering cholesterol. Related studies have shown that hesperidin has broad antibacterial spectrum on common food contamination. It has significant inhibitory effect on Bacillus subtilis, Salmonella typhimurium, Shigella bacteria, hemolytic streptococcus and Vibrio cholerae. Therefore, it is widely applied in food additives and food processing.
Hesperidin which has been found to be a potent chemopreventive agent in oral, urinary bladder, and colon carcinogenesis in animal models. Applied in food field, it is used as a flavour enhancer and sweetener in a wide variety of alcoholicbeverage, dessert foods and savory foods, applied in cosmetics, it can be added into toothpaste and mouth wash, applied in pharmaceutical field, it is mainly used to reducing the bitterness of in form. It also enhance the action of Vitamin C
Cat. No. | D490002A |
CAS. No. | 520-26-3 |
Molecular Formula | C28H34O15 |
Formula Weight | 610.56 g/mol |
Synonyms | 3',5,7-Trihydroxy 4'-methoxyflavanone 7-rutinoside; Hesperetin 7-rhamnoglucoside; Hesperitin-7-rutinoside |
Chemical Name | (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl}oxan-2-yl]oxy-2,3-dihydrochromen-4-one; (2S)-7-[[6-O-(6-Deoxy-a-L-mannopyranosyl)-ß-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-1-benzopyran-4-one |
Category | Reference Standards |
Product Stock Status | Please Enquire |