Keywords

• Buy 36062-04-1
• High Purity Tetrahydrocurcumin
• 36062-04-1 Tetrahydrocurcumin powder

Quick Details

• ProName: Buy 36062-04-1 High Purity Tetrahydroc...
• CasNo: 36062-04-1
• Molecular Formula: C21H24O6
• Appearance: White Powder
• Application: Hydrocurcumin has the effect of removi...
• DeliveryTime: Delivery time: 5-7 days after received...
• PackAge: 1kg with double plastic container insi...
• Port: Shanghai
• ProductionCapacity: 10000 Kilogram/Year
• Purity: 95%
• Storage: Stored in a clean, cool, dry area; kee...
• Transportation: Courier/ Express, air cargo and sea
• LimitNum: 100 Gram
• Plant of Origin: Curcumin Extract Tetrahydrocurcumin
• Testing Method: HPLC
• Product Ecification: 95%
• Heavy Metal: NMT 10PPM
• Voluntary Standards: usp /EP/CP
• Product Name: Curcumin Extract Tetrahydrocurcumin
• Test Method: HPLC
• Extract Method: Water & Ethanol Extration
• CAS No.: 36062-04-1
• Appearance: White Powder
• Active Ingredient: Tetrahydrocurcumin
• Application: Health Products
• Specification: 95%
• Shelf Life: 2 Years

Superiority

Buy 36062-04-1 High Purity Tetrahydrocurcumin 36062-04-1 Tetrahydrocurcumin powder

Tetrahydrocurcumin is a metabolite of curcumin (Item Nos. 81025 | 81025.1) that has diverse biological activities, including antioxidant, anti-inflammatory, anti-angiogenic, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay with an EC₅₀ value of 16.8 μM. Tetrahydrocurcumin (50 µM) inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) and COX-2 expression in RAW 264.7 cells. It also inhibits LPS-induced increases in TNF-α release when used at a concentration of 100 µM and increases in nitric oxide (NO) production and IL-6 levels in a concentration-dependent manner. Tetrahydrocurcumin reduces carrageenan-induced paw edema in rats (ED₅₀ = 20 mg/kg). It also reduces the formation of neocapillaries and decreases microvascular density as well as VEGF, VEGF receptor 2 (VEGFR2), and hypoxia-inducible factor-1α (HIF-1α) expression in a CaSki cervical cancer nude mouse xenograft model when administered at doses of 100, 300, and 500 mg/kg.

Tetrahydro Curcumin is a major metabolite of Curcumin (C838500) that has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress.

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